Chromatin Immunoprecipitation to Analyze DNA Binding Sites of HMGA2
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چکیده
منابع مشابه
Chromatin Immunoprecipitation to Analyze DNA Binding Sites of HMGA2
BACKGROUND HMGA2 is an architectonic transcription factor abundantly expressed during embryonic and fetal development and it is associated with the progression of malignant tumors. The protein harbours three basically charged DNA binding domains and an acidic protein binding C-terminal domain. DNA binding induces changes of DNA conformation and hence results in global overall change of gene exp...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2011
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0018837